A decade after a tragic mistake, Chas Chandler and occult investigator, John Constantine, set out to cure Chas's daughter, Trish, from a demonically induced coma. With the help of the mysterious Nightmare Nurse, the influential Queen of Angels, and the brutal Aztec God, Mictlantecuhtli, they just might have the chance to outsmart the demon Beroul and save Trish's soul.